HHNeuronTraubMiles91 Class Reference

Conductance based spiking neuron using Traubs modified HH model. More...

#include <HHNeuronTraubMiles91.h>

Inheritance diagram for HHNeuronTraubMiles91:

Collaboration diagram for HHNeuronTraubMiles91:

List of all members.

Public Member Functions

HHNeuronTraubMiles91 (float Rm=100e6, float Cm=2e-10, float Vresting=-0.06, float Vthresh=0.0, float Vinit=-0.06, float Trefract=5e-3, float Inoise=0.0, float Iinject=0.0)

Constructor to set the paramters.

double alpha_m (double V)

m - gate

double beta_m (double V)

double infty_m (double V)

double alpha_h (double V)

h - gate

double beta_h (double V)

double infty_h (double V)

double alpha_n (double V)

n - gate

double beta_n (double V)

double infty_n (double V)

virtual void derivatives (double t, const double y[], double f[])

virtual int reset (double dt)

Reset the neuron.

Public Attributes

float gbar_Na

Na peak conductance.

float E_Na

Na cannel reversal potential.

float gbar_K

K peak conductance.

float E_K

K cannel reversal potential.

Detailed Description

Conductance based spiking neuron using Traubs modified HH model.

This model is a modified version of Traub's model of Na/K currents for action potentials in hippocampal pyramidal cells, which was modified from HH equations to fit the kinetics of those neurons; the rate constants correspond to a temperature of 36 deg C

The model is based on a CbNeuron and includes the Traubs_HH_K_Channel and Traubs_HH_Na_Channel for action potetial generation.

INa = gNa * m^3 * h * (v-ENa) IKd = gKd * n^4 * (v-EK)

m' = (m_inf - m) / tau_m h' = (h_inf - h) / tau_h n' = (n_inf - n) / tau_n

v2 = v - Vtr

alpha_m = 0.32 * (13-v2) / ( exp((13-v2)/4) - 1) beta_m = 0.28 * (v2-40) / ( exp((v2-40)/5) - 1) tau_m = 1 / (alpha_m + beta_m) m_inf = alpha_m / (alpha_m + beta_m)

alpha_h = 0.128 * exp((17-v2)/18) beta_h = 4 / ( 1 + exp((40-v2)/5) ) tau_h = 1 / (alpha_h + beta_h) h_inf = alpha_h / (alpha_h + beta_h)

alpha_n = 0.032 * (15-v2) / ( exp((15-v2)/5) - 1) beta_n = 0.5 * exp((10-v2)/40) tau_n = 1 / (alpha_n + beta_n) n_inf = alpha_n / (alpha_n + beta_n)

HH parameters:

gNa = 0.1 S/cm2 gKd = 0.03 S/cm2 ENa = 50 mV EK = -90 mV Vtr = -63 mV (adjusts threshold to around -50 mV)

Definition at line 49 of file HHNeuronTraubMiles91.h.

Constructor & Destructor Documentation

HHNeuronTraubMiles91::HHNeuronTraubMiles91	(	float	Rm = `100e6`,
		float	Cm = `2e-10`,
		float	Vresting = `-0.06`,
		float	Vthresh = `0.0`,
		float	Vinit = `-0.06`,
		float	Trefract = `5e-3`,
		float	Inoise = `0.0`,
		float	Iinject = `0.0`
	)			`[inline]`

Constructor to set the paramters.

Definition at line 68 of file HHNeuronTraubMiles91.h.

References ODESystemBasedSpikingNeuron::Cm, E_K, E_Na, gbar_K, gbar_Na, ODESystemBasedSpikingNeuron::Iinject, ODESystemBasedSpikingNeuron::Inoise, ODESystemBasedSpikingNeuron::Rm, ODESystemBasedSpikingNeuron::Trefract, ODESystemBasedSpikingNeuron::Vinit, ODESystemBasedSpikingNeuron::Vresting, and ODESystemBasedSpikingNeuron::Vthresh.

Member Function Documentation

double HHNeuronTraubMiles91::alpha_m ( double V ) [inline]

m - gate

Definition at line 94 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), and infty_m().

double HHNeuronTraubMiles91::beta_m ( double V ) [inline]

Definition at line 97 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), and infty_m().

double HHNeuronTraubMiles91::infty_m ( double V ) [inline]

Definition at line 100 of file HHNeuronTraubMiles91.h.

References alpha_m(), and beta_m().

Referenced by reset().

Here is the call graph for this function:

double HHNeuronTraubMiles91::alpha_h ( double V ) [inline]

h - gate

Definition at line 105 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), and infty_h().

double HHNeuronTraubMiles91::beta_h ( double V ) [inline]

Definition at line 108 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), and infty_h().

double HHNeuronTraubMiles91::infty_h ( double V ) [inline]

Definition at line 111 of file HHNeuronTraubMiles91.h.

References alpha_h(), and beta_h().

Referenced by reset().

Here is the call graph for this function:

double HHNeuronTraubMiles91::alpha_n ( double V ) [inline]

n - gate

Definition at line 116 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), and infty_n().

double HHNeuronTraubMiles91::beta_n ( double V ) [inline]

Definition at line 119 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), and infty_n().

double HHNeuronTraubMiles91::infty_n ( double V ) [inline]

Definition at line 122 of file HHNeuronTraubMiles91.h.

References alpha_n(), and beta_n().

Referenced by reset().

Here is the call graph for this function:

virtual void HHNeuronTraubMiles91::derivatives	(	double	t,
		const double	y[],
		double	f[]
	)			`[inline, virtual]`

Implements odeiv::ODESystem.

Definition at line 126 of file HHNeuronTraubMiles91.h.

References alpha_h(), alpha_m(), alpha_n(), beta_h(), beta_m(), beta_n(), ODESystemBasedSpikingNeuron::Cm, E_K, E_Na, ODESystemBasedSpikingNeuron::G0, gbar_K, gbar_Na, and ODESystemBasedSpikingNeuron::I0.

Here is the call graph for this function:

virtual int HHNeuronTraubMiles91::reset ( double dt ) [inline, virtual]

Reset the neuron.

Reimplemented from SimObject.

Definition at line 148 of file HHNeuronTraubMiles91.h.

References E_K, E_Na, ODESystemBasedSpikingNeuron::Em, gbar_K, gbar_Na, infty_h(), infty_m(), infty_n(), SingleOutputSpikeSender::reset(), ODESystemBasedSpikingNeuron::Rm, ODESystemBasedSpikingNeuron::Vinit, and ODESystemBasedSpikingNeuron::Vresting.

Here is the call graph for this function:

Member Data Documentation

float HHNeuronTraubMiles91::gbar_Na

Na peak conductance.

Definition at line 56 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), HHNeuronTraubMiles91(), and reset().

float HHNeuronTraubMiles91::E_Na

Na cannel reversal potential.

Definition at line 59 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), HHNeuronTraubMiles91(), and reset().

float HHNeuronTraubMiles91::gbar_K

K peak conductance.

Definition at line 62 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), HHNeuronTraubMiles91(), and reset().

float HHNeuronTraubMiles91::E_K

K cannel reversal potential.

Definition at line 65 of file HHNeuronTraubMiles91.h.

Referenced by derivatives(), HHNeuronTraubMiles91(), and reset().

The documentation for this class was generated from the following file:

/home/tnatschl/PCSIM-Sandbox/pcsim/pcsim/simobjects/HHNeuronTraubMiles91.h


Public Member Functions
	HHNeuronTraubMiles91 (float Rm=100e6, float Cm=2e-10, float Vresting=-0.06, float Vthresh=0.0, float Vinit=-0.06, float Trefract=5e-3, float Inoise=0.0, float Iinject=0.0)
	Constructor to set the paramters.
double	alpha_m (double V)
	m - gate
double	beta_m (double V)
double	infty_m (double V)
double	alpha_h (double V)
	h - gate
double	beta_h (double V)
double	infty_h (double V)
double	alpha_n (double V)
	n - gate
double	beta_n (double V)
double	infty_n (double V)
virtual void	derivatives (double t, const double y[], double f[])
virtual int	reset (double dt)
	Reset the neuron.
Public Attributes
float	gbar_Na
	Na peak conductance.
float	E_Na
	Na cannel reversal potential.
float	gbar_K
	K peak conductance.
float	E_K
	K cannel reversal potential.